mtDNA Testing

How common is mtDNA heteroplasmy?

All mitochondrial DNA (mtDNA) mutations go through a state of heteroplasmy. The frequency of heteroplasmy is then equal to or greater than mtDNA mutation rates. Note that population geneticists usually calculate mutation rates using those [...]

How is mtDNA heteroplasmy inherited?

In each generation, it is possible for the child to inherit the heteroplasmic genome, only the ancestral genome, or only the descendant genome. For each generation, if the mother has a heteroplasmy, each of her [...]

How do mitochondrial mutations occur?

Every human cell contains hundreds of mitochondria. Each mitochondrion in a cell contains multiple copies of its own DNA (mtDNA). A new mitochondrial mutation occurs in only one copy of the mtDNA in one mitochondria [...]